MAPKAP1 anticorps (AA 250-522)

N° du produit ABIN5027356

L’anticorps Lapin Polyclonal anti-MAPKAP1 a été validé pour WB. Il convient pour détecter MAPKAP1 dans des échantillons de Humain.

Aperçu rapide pour MAPKAP1 anticorps (AA 250-522) (ABIN5027356)

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAPKAP1 anticorps

Épitope: AA 250-522

Purification: Protein A Chromatography

Immunogène: A partial length recombinant Mip1 protein (amino acids 250-522) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-3 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MAPKAP1

Antigène: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Autre désignation: SAPK interacting proten 1/Mip1

Sujet: Stress-activated map kinase (SAPK )-interacting protein 1, also called as Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1), belongs to Stress-activated map kinase interacting protein 1 (SIN1) family. It is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors and also plays a critical role in AKT1 'Ser-473'phosphorylation. Except isoform 4 from its 6 isoforms , all can be incorporated into the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. It is ubiquitously expressed in heart and skeletal muscle. Diseases associated with MAPKAP1 include bronchiolitis obliterans organizing pneumonia and nephrogenic systemic fibrosis.

Poids moléculaire: 50 kDa

ID gène: 79109

UniProt: Q9BPZ7

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events