MERS-Coronavirus Spike anticorps

N° du produit ABIN5027657

Détail du produit anti-MERS-Coronavirus Spike anticorps

Antigène: MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))

Reactivité: Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MERS-Coronavirus Spike est non-conjugé

Application: Western Blotting (WB)

Purification: Protein G Chromatography

Immunogène: A recombinant protein fragment of MERS-CoV Spike (S) protein was used as the immunogen for this antibody.

Clone: ABM4A80

Isotype: IgG2b kappa

Information d'application

Indications d'application: WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MERS-Coronavirus Spike

Antigène: MERS-Coronavirus Spike (MERS-CoV S) (MERS-Coronavirus Spike Protein (MERS-CoV S))

Autre désignation: MERS-CoV Spike (S) protein (MERS-CoV S Produits)

Classe de substances: Viral Protein

Sujet: The MERS-CoV spike (S) protein is a type I transmembrane glycoprotein which contains 1353 amino acids and can be cleaved into two subunit S1 and S2. It forms large protruding spikes on the surface of the virus. The S1 subunit which contains RBD is responsible for binding to Dipeptidyl peptidase 4, which serves as the host cell receptor of MERS-CoV and S2 mediates the membrane fusion. In this process, heptad repeats 1 and 2 (HR1 and HR2) of the S protein assemble into a complex called six-helix bundle (6-HB) fusion core structure, which represents a key membrane fusion architecture. Importantly, the S protein is considered a key component of vaccines against coronavirus infection, including severe acute respiratory syndrome (SARS).

Poids moléculaire: 28 kDa

UniProt: W5ZZU6