SQSTM1 anticorps (AA 1-440)

N° du produit ABIN522359

L’anticorps Souris Monoclonal anti-SQSTM1 a été validé pour WB et ELISA. Il convient pour détecter SQSTM1 dans des échantillons de Humain. Il y a 4+ publications disponibles.

Aperçu rapide pour SQSTM1 anticorps (AA 1-440) (ABIN522359)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1C9

Détail du produit anti-SQSTM1 anticorps

Épitope: AA 1-440

Fonction: Mouse monoclonal antibody raised against a full-length recombinant SQSTM1.

Séquence: MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SQSTM1 (ABIN522359)

Myeku, Clelland, Emrani, Kukushkin, Yu, Goldberg, Duff: "Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." dans: Nature medicine, Vol. 22, Issue 1, pp. 46-53, (2016) (PubMed).

Notte, Ninane, Arnould, Michiels: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." dans: Cell death & disease, Vol. 4, pp. e638, (2013) (PubMed).

Cosse, Rommelaere, Ninane, Arnould, Michiels: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." dans: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, (2010) (PubMed).

Kirkin, Lamark, Sou, Bjørkøy, Nunn, Bruun, Shvets, McEwan, Clausen, Wild, Bilusic, Theurillat, Øvervatn, Ishii, Elazar, Komatsu, Dikic, Johansen: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." dans: Molecular cell, Vol. 33, Issue 4, pp. 505-16, (2009) (PubMed).

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: SQSTM1

Sujet: Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B

ID gène: 8878

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy