SQSTM1 anticorps (Sequestosome 1) (AA 1-440)

Details for Product anti-SQSTM1 Antibody No. ABIN522359, Fournisseur: Connectez-vous pour afficher
Antigène
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sequestosome 1 L homeolog
  • SQSTM1
  • sqstm1
  • Sqstm1
  • sqstm1.L
Épitope
AA 1-440
69
42
40
36
36
20
19
17
17
16
15
14
11
9
9
8
7
6
5
5
4
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivité
Humain
398
194
139
8
5
5
5
5
4
4
2
2
2
2
2
1
1
1
1
Hôte
Souris
338
52
6
3
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp SQSTM1 est non-conjugé
20
19
19
12
12
12
7
7
7
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
335
133
109
98
86
74
38
38
28
22
20
13
4
3
2
1
Options
Fournisseur
Connectez-vous pour afficher
N° du produit (Fournisseur)
Connectez-vous pour afficher
Immunogène SQSTM1 (AAH03139.1, 1 a.a. ~ 440 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL
Clone 1C9
Isotype IgG3 kappa
 Réactivité croisée Humain
Plasmids, Primers & others Plasmids, Primers & others SQSTM1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation SQSTM1 (SQSTM1 Antibody Extrait)
Sujet Full Gene Name: sequestosome 1
Synonyms: A170,OSIL,PDB3,ZIP3,p60,p62,p62B
ID gène 8878
Pathways Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
Indications d'application Optimal working dilution should be determined by the investigator.
Commentaires

Product Quality tested by: Antibody Reactive Against Recombinant Protein.

Restrictions For Research Use only
Buffer In 1x PBS, pH 7.4
Conseil sur la manipulation Aliquot to avoid repeated freezing and thawing.
Stock -20 °C
Stockage commentaire Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Images (Fournisseur)
ELISA image for anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibody (ABIN522359) Detection limit for recombinant GST tagged SQSTM1 is approximately 3ng/ml as a captur...
 image for anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibody (ABIN522359) Western Blot detection against Immunogen (74.14 KDa) .
Produit citée dans: Myeku, Clelland, Emrani, Kukushkin, Yu, Goldberg, Duff: "Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling." dans: Nature medicine, Vol. 22, Issue 1, pp. 46-53, 2016 (PubMed).

Notte, Ninane, Arnould, Michiels: "Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation." dans: Cell death & disease, Vol. 4, pp. e638, 2013 (PubMed).

Cosse, Rommelaere, Ninane, Arnould, Michiels: "BNIP3 protects HepG2 cells against etoposide-induced cell death under hypoxia by an autophagy-independent pathway." dans: Biochemical pharmacology, Vol. 80, Issue 8, pp. 1160-9, 2010 (PubMed).

Kirkin, Lamark, Sou, Bjørkøy, Nunn, Bruun, Shvets, McEwan, Clausen, Wild, Bilusic, Theurillat, Øvervatn, Ishii, Elazar, Komatsu, Dikic, Johansen: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." dans: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).

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