FCGR3A anticorps (PE)

N° du produit ABIN535935

Détail du produit anti-FCGR3A anticorps (PE)

Antigène: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FCGR3A est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Fonction: Mouse monoclonal antibody raised against native FCGR3A.

Specificité: This antibody reacts with CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 KDa, expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB, 48 KDa, mainly expressed on neutrophils).

Réactivité croisée: Humain, Non-Human Primate

Immunogène: Native purified FCGR3A from normal human peripheral blood granulocytes.

Clone: LNK16

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry (20 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-FCGR3A (PE) (ABIN535935)

Boyle: "Human macrophages kill human mesangial cells by Fas-L-induced apoptosis when triggered by antibody via CD16." dans: Clinical and experimental immunology, Vol. 137, Issue 3, pp. 529-37, (2004) (PubMed).

Arase, Arase, Hirano, Yokosuka, Sakurai, Saito: "IgE-mediated activation of NK cells through Fc gamma RIII." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 6, pp. 3054-8, (2003) (PubMed).

Détails sur FCGR3A

Antigène: FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))

Autre désignation: FCGR3A (FCGR3A Produits)

Synonymes: anticorps CD16, anticorps CD16A, anticorps FCG3, anticorps FCGR3, anticorps FCGRIII, anticorps FCR-10, anticorps FCRIII, anticorps FCRIIIA, anticorps IGFR3, anticorps Fcgr4, anticorps Fc fragment of IgG receptor IIIa, anticorps FCGR3A, anticorps Fcgr3a

ID gène: 2214