Rabbit polyclonal antibody raised against synthetic peptide of MAT2A.
Specificité
This antibody has 100 % homology to both the MAT1A and MAT2A proteins. This antibody recognizes recombinant MAT2A protein, but specificity for MAT1A has not been tested.
Réactivité croisée
Boeuf (Vache), Humain, Singe, Primate, Rat, Poisson zèbre (Danio rerio)
Immunogène
A synthetic peptide corresponding to amino acids 100-200 of human MAT2A.
MAT2A
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot (2 μg/mL) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (30 % glycerol, 0.09 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for short term. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Ramani, Yang, Xia, Ara, Mato, Lu: "Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta." dans: Hepatology (Baltimore, Md.), Vol. 47, Issue 2, pp. 521-31, (2008) (PubMed).
Rodríguez, Boukaba, Sandoval, Georgieva, Latasa, García-Trevijano, Serviddio, Nakamura, Avila, Sastre, Torres, Mato, López-Rodas: "Transcription of the MAT2A gene, coding for methionine adenosyltransferase, is up-regulated by E2F and Sp1 at a chromatin level during proliferation of liver cells." dans: The international journal of biochemistry & cell biology, Vol. 39, Issue 4, pp. 842-50, (2007) (PubMed).
Liu, Wu, Zhu, He, Wu, Liu: "Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 37, Issue 5, pp. 376-88, (2007) (PubMed).
Antigène
MAT2A
(Methionine Adenosyltransferase II, alpha (MAT2A))