PKD2 anticorps (C-Term)

N° du produit ABIN543268

Détail du produit anti-PKD2 anticorps

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit polyclonal antibody raised against synthetic peptide of PKD2.

Réactivité croisée: Humain

Immunogène: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PKD2.

Information d'application

Indications d'application: Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-PKD2 (ABIN543268)

Gargalionis, Korkolopoulou, Farmaki, Piperi, Dalagiorgou, Adamopoulos, Levidou, Saetta, Fragkou, Tsioli, Kiaris, Zizi-Serbetzoglou, Karavokyros, Papavassiliou, Tsavaris, Patsouris, Basdra et al.: "Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. ..." dans: International journal of cancer. Journal international du cancer, Vol. 136, Issue 7, pp. 1515-27, (2015) (PubMed).

Varela, Piperi, Sigala, Agrogiannis, Davos, Andri, Manopoulos, Tsangaris, Basdra, Papavassiliou: "Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity." dans: Scientific reports, Vol. 5, pp. 13461, (2015) (PubMed).

Stayner, Zhou: "Polycystin channels and kidney disease." dans: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, (2001) (PubMed).

Watnick, He, Wang, Liang, Parfrey, Hefferton, St George-Hyslop, Germino, Pei: "Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations." dans: Nature genetics, Vol. 25, Issue 2, pp. 143-4, (2000) (PubMed).

Lehtonen, Ora, Olkkonen, Geng, Zerial, Somlo, Lehtonen: "In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2." dans: The Journal of biological chemistry, Vol. 275, Issue 42, pp. 32888-93, (2000) (PubMed).

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2 (PKD2 Produits)

Synonymes: anticorps APKD2, anticorps PC2, anticorps PKD4, anticorps Pc-2, anticorps TRPP2, anticorps C030034P18Rik, anticorps RGD1559992, anticorps pkd2, anticorps trpp2, anticorps Cup, anticorps PKD2L1, anticorps polycystin 2, transient receptor potential cation channel, anticorps polycystic kidney disease 2, anticorps Polycystin-2, anticorps polycystin 2, transient receptor potential cation channel L homeolog, anticorps PKD2, anticorps Pkd2, anticorps pkd-2, anticorps pkd2.L, anticorps pkd2

ID gène: 5311

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity