EIF2B3
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
van der Knaap, Leegwater, Könst, Visser, Naidu, Oudejans, Schutgens, Pronk: "Mutations in each of the five subunits of translation initiation factor eIF2B can cause leukoencephalopathy with vanishing white matter." dans: Annals of neurology, Vol. 51, Issue 2, pp. 264-70, (2002) (PubMed).
Gomez, Pavitt et al.: "Identification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation ..." dans: Molecular and cellular biology, Vol. 20, Issue 11, pp. 3965-76, (2000) (PubMed).
Kruger, Beger, Li, Welch, Tritz, Leavitt, Barber, Wong-Staal: "Identification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approach." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 15, pp. 8566-71, (2000) (PubMed).