PFKFB3 anticorps (C-Term)

N° du produit ABIN5514397

L’anticorps anti-PFKFB3 Polyclonal Lapin est utilisé pour la détection de PFKFB3 dans des échantillons de Humain, Rat, Souris, Cobaye, Boeuf (Vache), Cheval, Lapin et Chien. Il a été validé pour WB.

Aperçu rapide pour PFKFB3 anticorps (C-Term) (ABIN5514397)

Antigène: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Reactivité: Humain, Rat, Souris, Cobaye, Boeuf (Vache), Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKFB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PFKFB3 anticorps

Épitope: C-Term

Fonction: PFKFB3 Antibody - C-terminal region

Séquence: VESVCTHRER SEDAKKGPNP LMRRNSVTPL ASPEPTKKPR INSFEEHVAS

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against F263. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human F263

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56582-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PFKFB3

Antigène: PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))

Autre désignation: PFKFB3

Sujet:

Background Information: The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

Alternative Symbols: PFK2, IPFK2, iPFK-2

Protein Name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

Poids moléculaire: 57kDa

ID gène: 5209

UniProt: Q16875

Pathways: AMPK Signaling, Regulation of Carbohydrate Metabolic Process