C5AR1 anticorps (N-Term)

N° du produit ABIN5514594

Cet anticorps Lapin Polyclonal détecte spécifiquement C5AR1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour C5AR1 anticorps (N-Term) (ABIN5514594)

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C5AR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-C5AR1 anticorps

Épitope: N-Term

Séquence: SFNYTTPDYG HYDDKDTLDL NTPVDKTSNT LRVPDILALV IFAVVFLVGV

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human C5AR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: C5AR1

Sujet: This gene encodes a member of the proline-rich protein family. The encoded protein has multiple proposed functions, including roles in pain suppression, penile erection, and protection of the eye surface. The QRFSR pentapeptide, known as opiorphin, is derived from the N-terminal of this protein. Opiorphin inhibits the enkephalin-inactivating peptidases neprilysin and aminopeptidase N, and this activity is thought to reduce sensitivity to painful stimuli by effecting enkephalin-related activation of opioid-dependent pathways. Opiorphin may also act as an anti-depressant. Alternative splicing results in multiple transcript variants.

Alias Symbols: BPLP, PRL1, opiorphin,

Protein Size: 350

ID gène: 58503

NCBI Accession: NM_001736, NP_001727

UniProt: P21730

Pathways: Système du Complément