Phospholipase C gamma 2 anticorps (Middle Region)

N° du produit ABIN5514741

Cet anticorps Lapin Polyclonal détecte spécifiquement Phospholipase C gamma 2 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour Phospholipase C gamma 2 anticorps (Middle Region) (ABIN5514741)

Antigène: Phospholipase C gamma 2 (PLCG2)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C gamma 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Phospholipase C gamma 2 anticorps

Épitope: Middle Region

Séquence: ETHLRCAEFE LRLTDPVPNP NPHESKPWYY DSLSRGEAED MLMRIPRDGA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PLCG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human PLCG2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Phospholipase C gamma 2

Antigène: Phospholipase C gamma 2 (PLCG2)

Autre désignation: PLCG2

Sujet: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Alias Symbols: PLCG2,

Protein Interaction Partner: UBC, ZNF512B, ERBB2, EGFR, PRKCA, PLD1, IRS1, BLNK, LAT2, LIME1, GAB2, DAPP1, PRKD1, CBLB, GAB1, KHDRBS1, LAT, SH3BP2, LCP2, TEC, SHC1, PLCG2, SYK, BTK, KDR, BLK, ITK, LYN, FLT1, NPM1, LCK, JAK2, JAK1, FCER1G, HCK, FYN, EPOR, CD19, PLXNB1, VAV1, PTPN11,

Protein Size: 1265

ID gène: 5336

NCBI Accession: NM_002661, NP_002652

UniProt: P16885

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling