Stanniocalcin 2 anticorps (N-Term)

N° du produit ABIN5515182

Cet anticorps Lapin Polyclonal détecte spécifiquement Stanniocalcin 2 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Stanniocalcin 2 anticorps (N-Term) (ABIN5515182)

Antigène: Stanniocalcin 2 (STC2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Stanniocalcin 2 anticorps

Épitope: N-Term

Séquence: ATFDPARGTD ATNPPEGPQD RSSQQKGRLS LQNTAEIQHC LVNAGDVGCG

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Stanniocalcin 2

Antigène: Stanniocalcin 2 (STC2)

Autre désignation: STC2

Sujet: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Alias Symbols: STC-2, STCRP

Protein Size: 302

ID gène: 8614

NCBI Accession: NM_003714, NP_003705

UniProt: O76061

Pathways: Hormone Activity, ER-Nucleus Signaling, SARS-CoV-2 Protein Interactome