DUSP2 anticorps (C-Term)

N° du produit ABIN5515662

Détail du produit anti-DUSP2 anticorps

Antigène: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DUSP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SATICLAYLM QSRRVRLDEA FDFVKQRRGV ISPNFSFMGQ LLQFETQVLC

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DUSP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DUSP2

Antigène: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Autre désignation: DUSP2 (DUSP2 Produits)

Synonymes: anticorps zgc:91929, anticorps wu:fj40g04, anticorps PAC-1, anticorps PAC1, anticorps dual specificity phosphatase 2, anticorps dusp2, anticorps DUSP2, anticorps Dusp2

Sujet: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Alias Symbols: PAC1, PAC-1

Protein Size: 314

ID gène: 1844

NCBI Accession: NM_004418, NP_004409

UniProt: Q05923