MAP2K4 anticorps (C-Term)

N° du produit ABIN5516102

Cet anticorps anti-MAP2K4 est un anticorps Lapin Polyclonal détectant MAP2K4 dans WB. Adapté pour Humain.

Aperçu rapide pour MAP2K4 anticorps (C-Term) (ABIN5516102)

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K4 anticorps

Épitope: C-Term

Séquence: NLKIIHRDIK PSNILLDRSG NIKLCDFGIS GQLVDSIAKT RDAGCRPYMA

Attributs du produit: This is a rabbit polyclonal antibody against MAP2K4. It was validated on Western Blot.

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAP2K4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP2K4

Antigène: MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))

Autre désignation: MAP2K4

Sujet: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.

Alias Symbols: JNKK, JNKK1, MAPKK4, MEK4, MKK4, PRKMK4, SAPKK-1, SAPKK1, SEK1, SERK1

Protein Interaction Partner: UBC, EGFR, GEMIN5, MAP3K5, MAP3K1, GCH1, MAPK10, MAPK9, MAPK8, MAPK1, ARRB2, ARRB1, MAP3K7, RBBP8, JUN, MAP2K7, APP, MAP3K2, MAPK14, AKT1, LRRK2, MAP2K4, MAP2K6, MAP3K4, MAP3K3, PML, BLNK, ITCH, MAPK8IP3, ZAK, SPAG9, TRIB1, MAP3K14, CFLAR, MAPK12, EFNA4,

Protein Size: 399

ID gène: 6416

NCBI Accession: NM_003010, NP_003001

UniProt: P45985

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling