MAP2K7 anticorps (N-Term)

N° du produit ABIN5516106

Cet anticorps Lapin Polyclonal détecte spécifiquement MAP2K7 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MAP2K7 anticorps (N-Term) (ABIN5516106)

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K7 anticorps

Épitope: N-Term

Fonction: MAP2K7 Antibody - N-terminal region

Séquence: LNLDISPQRP RPTLQLPLAN DGGSRSPSSE SSPQHPTPPA RPRHMLGLPS

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MAP2K7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP81182-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MAP2K7

Sujet:

Background Information: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Gene Name: mitogen-activated protein kinase kinase 7

Alternative Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4

Protein Name: dual specificity mitogen-activated protein kinase kinase 7

Poids moléculaire: 50 kDa

ID gène: 5609

NCBI Accession: NP_660186

UniProt: O14733

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling