MR1 anticorps (N-Term)

N° du produit ABIN5516857

L’anticorps anti-MR1 Polyclonal Lapin est utilisé pour la détection de MR1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MR1 anticorps (N-Term) (ABIN5516857)

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MR1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MR1 anticorps

Épitope: N-Term

Fonction: MR1 Antibody - N-terminal region

Séquence: RTHSLRYFRL GVSDPIHGVP EFISVGYVDS HPITTYDSVT RQKEPRAPWM

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MR1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78052-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MR1

Antigène: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Autre désignation: MR1

Sujet:

Background Information: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Gene Name: major histocompatibility complex, class I-related

Alternative Symbols: HLALS

Protein Name: major histocompatibility complex class I-related gene protein

Poids moléculaire: 39 kDa

ID gène: 3140

NCBI Accession: NP_001181928

UniProt: Q95460

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints