Nyctalopin anticorps (Middle Region)

N° du produit ABIN5517443

Détail du produit anti-Nyctalopin anticorps

Antigène: Nyctalopin (NYX)

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nyctalopin est non-conjugé

Application: Western Blotting (WB)

Séquence: GSGRVTDVPC ASPGSVAGLD LSQVTFGRSS DGLCVDPEEL NLTTSSPGPS

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human NYX

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Nyctalopin

Antigène: Nyctalopin (NYX)

Autre désignation: NYX (NYX Produits)

Synonymes: anticorps MGC84276, anticorps CLRP, anticorps CSNB1, anticorps CSNB1A, anticorps CSNB4, anticorps NBM1, anticorps CLNP, anticorps nob, anticorps RGD1561300, anticorps nyctalopin, anticorps nyctalopin L homeolog, anticorps uncharacterized LOC491837, anticorps NYX, anticorps nyx.L, anticorps LOC491837, anticorps nyx, anticorps Nyx

Sujet: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Alias Symbols: CLRP, NBM1, CSNB1, CSNB4, CSNB1A

Protein Size: 481

ID gène: 60506

NCBI Accession: NM_022567, NP_072089

UniProt: Q9GZU5