RSPO1 anticorps (C-Term)

N° du produit ABIN5517492

Cet anticorps Lapin Polyclonal détecte spécifiquement RSPO1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour RSPO1 anticorps (C-Term) (ABIN5517492)

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSPO1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RSPO1 anticorps

Épitope: C-Term

Séquence: RCTVRRVPCP EGQKRRKGGQ GRRENANRNL ARKESKEAGA GSRRRKGQQQ

Homologie: Cow: 85%, Dog: 92%, Goat: 85%, Horse: 92%, Human: 100%, Rabbit: 86%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RSPO1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RSPO1

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Autre désignation: RSPO1

Sujet: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.

Alias Symbols: RSPO, CRISTIN3

Protein Interaction Partner: Znrf3, LGR4, RSPO4, RSPO2, RSPO3, RNF43,

Protein Size: 236

ID gène: 284654

NCBI Accession: NM_001242909, NP_001229838