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VEGFA anticorps (AA 27-214)

VEGFA Reactivité: Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5518798
  • Antigène Voir toutes VEGFA Anticorps
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Épitope
    • 19
    • 15
    • 15
    • 15
    • 15
    • 15
    • 10
    • 7
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    • 6
    • 6
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    • 3
    • 3
    • 3
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    • 1
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    AA 27-214
    Reactivité
    • 156
    • 125
    • 99
    • 24
    • 20
    • 19
    • 19
    • 16
    • 12
    • 7
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 1
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    • 1
    Rat
    Hôte
    • 203
    • 54
    • 13
    • 1
    • 1
    Lapin
    Clonalité
    • 214
    • 57
    • 1
    Polyclonal
    Conjugué
    • 123
    • 41
    • 25
    • 12
    • 5
    • 5
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    Cet anticorp VEGFA est non-conjugé
    Application
    • 206
    • 93
    • 65
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    • 27
    • 22
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    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor A(Vegfa) detection. Tested with WB in Mouse,Rat.
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor A(Vegfa) detection. Tested with WB in Mouse,Rat.
    Gene Name: vascular endothelial growth factor A
    Protein Name: Vascular endothelial growth factor A
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived mouse VEGF recombinant protein (Position: A27-R214). Mouse VEGF shares 89.4% and 98.4% amino acid (aa) sequence identity with human and rat VEGF, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product VEGFA Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Zhang, Chu, Liu, Coates, Shang, Li: "Deer thymosin beta 10 functions as a novel factor for angiogenesis and chondrogenesis during antler growth and regeneration." dans: Stem cell research & therapy, Vol. 9, Issue 1, pp. 166, (2019) (PubMed).

    Liu, Kuang, Wu, Jin, Sun: "A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo." dans: Scientific reports, Vol. 6, pp. 26722, (2018) (PubMed).

    Qin, Ke, Zhou, Wang, Liang, Wang, Yang, Gao, Ye, Kumar, Wang: "Metastasis-Associated Protein 1 Deficiency Results in Compromised Pulmonary Alveolar Capillary Angiogenesis in Mice." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 3932-3941, (2018) (PubMed).

    Fang, Li, Qiao, Guo, Miao: "Neuroprotective effect of total flavonoids from Ilex pubescens against focal cerebral ischemia/reperfusion injury in rats." dans: Molecular medicine reports, Vol. 16, Issue 5, pp. 7439-7449, (2018) (PubMed).

    Yang, Zhang, Li, Wen: "MALAT1 enhanced the proliferation of human osteoblasts treated with ultra‑high molecular weight polyethylene by targeting VEGF via miR‑22‑5p." dans: International journal of molecular medicine, Vol. 41, Issue 3, pp. 1536-1546, (2018) (PubMed).

    Luo, Zhu, Wang, Yu, Zhou: "MicroRNA-126 affects ovarian cancer cell differentiation and invasion by modulating expression of vascular endothelial growth factor." dans: Oncology letters, Vol. 15, Issue 4, pp. 5803-5808, (2018) (PubMed).

    Lu, Shi, Ma, Wang, Liu, Chuai, Song, Münsterberg, Cao, Yang: "Proper autophagy is indispensable for angiogenesis during chick embryo development." dans: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 13, pp. 1742-54, (2017) (PubMed).

    Gao, Chen, Gao, Wang, Sun, Yang: "CD47 deficiency in tumor stroma promotes tumor progression by enhancing angiogenesis." dans: Oncotarget, Vol. 8, Issue 14, pp. 22406-22413, (2017) (PubMed).

    Zhang, Yin, Ding, Zhang, Gao: "Vitamin K2 Ameliorates Damage of Blood Vessels by Glucocorticoid: a Potential Mechanism for Its Protective Effects in Glucocorticoid-induced Osteonecrosis of the Femoral Head in a Rat Model." dans: International journal of biological sciences, Vol. 12, Issue 7, pp. 776-85, (2017) (PubMed).

    Wang, Jiang, Xue: "Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1." dans: African health sciences, Vol. 16, Issue 2, pp. 542-53, (2017) (PubMed).

    Huang, Duan, Qian, Fan, Lv, Zhang, Han, Wu, Guo, Hu, Du, Chen, Jin: "Corrigendum: IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma." dans: Scientific reports, Vol. 7, pp. 39566, (2017) (PubMed).

    Zhang, Liu, Liu, Zhou, Song, Cao, An: "miR-182 aids in receptive endometrium development in dairy goats by down-regulating PTN expression." dans: PLoS ONE, Vol. 12, Issue 7, pp. e0179783, (2017) (PubMed).

    Dai, Jia, Wang, Yang, Jiang, Chu: "Epidermal growth factor receptor transactivation is involved in the induction of human hepatoma SMMC7721 cell proliferation by insufficient radiofrequency ablation." dans: Oncology letters, Vol. 14, Issue 2, pp. 2463-2467, (2017) (PubMed).

    Zhang, Li, Zheng, Lin, Zhang, Zhang: "Inhibition of angiogenesis by arsenic trioxide via TSP-1-TGF-β1-CTGF-VEGF functional module in rheumatoid arthritis." dans: Oncotarget, Vol. 8, Issue 43, pp. 73529-73546, (2017) (PubMed).

    Zhong, Huang, Su, Zhang, Xu, Gong, Chen, Zeng, Chen, Zhou: "Downregulation of miR-199a-5p promotes prostate adeno-carcinoma progression through loss of its inhibition of HIF-1α." dans: Oncotarget, Vol. 8, Issue 48, pp. 83523-83538, (2017) (PubMed).

    Wang, Wang, Li, Wu, Liu, Yang, Ji, Ji, Li: "The Neuropilin-1 Inhibitor, ATWLPPR Peptide, Prevents Experimental Diabetes-Induced Retinal Injury by Preserving Vascular Integrity and Decreasing Oxidative Stress." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142571, (2016) (PubMed).

    Yang, Wang, Guo, Wang: "Correlation and Significance of Urinary Soluble Fas and Vascular Endothelial Growth Factor in Bladder Urothelial Cancer." dans: Disease markers, Vol. 2015, pp. 383509, (2016) (PubMed).

    Yuan, Christina, Guo, Chu, Liu, Yan: "Involvement of MicroRNA-210 Demethylation in Steroid-associated Osteonecrosis of the Femoral Head." dans: Scientific reports, Vol. 6, pp. 20046, (2016) (PubMed).

    Zhang, Wang, Dai, Cai, Zhan, Gang, Hu, Xia, Zhang: "Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma." dans: Oncotarget, Vol. 7, Issue 7, pp. 8043-54, (2016) (PubMed).

    Song, Tao, Wang, Wang, Wei, Shen, Zhou: "Effect of bone mesenchymal stem cells transplantation on the micro-environment of early osteonecrosis of the femoral head." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14528-34, (2016) (PubMed).

  • Antigène
    VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
    Autre désignation
    Vegfa (VEGFA Produits)
    Synonymes
    anticorps MVCD1, anticorps VEGF, anticorps VPF, anticorps Vegf, anticorps Vegf120, anticorps Vegf164, anticorps Vegf188, anticorps Vpf, anticorps vegf, anticorps vegfa, anticorps wu:fj82c06, anticorps VEGF-A, anticorps VEGF164, anticorps eVEGF120, anticorps eVEGF164, anticorps vegf-a, anticorps vpf, anticorps vefg, anticorps si:dkey-14d8.3, anticorps wu:fd42e02, anticorps vascular endothelial growth factor A, anticorps vascular endothelial growth factor Aa, anticorps vascular endothelial growth factor A L homeolog, anticorps vascular endothelial growth factor Ab, anticorps VEGFA, anticorps Vegfa, anticorps vegfaa, anticorps vegfa.L, anticorps vegfa, anticorps vegfab
    Sujet
    VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. And VEGF induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. This gene can also regulate haematopoietic stem cell survival by an internal autocrine loop mechanism. What's more, it also stimulates neurogenesis in vitro and in vivo.

    Synonyms: MVCD1 | P15692 | Vascular endothelial growth factor | Vascular permeability factor | VEGF A | VEGF-A | VEGFA | VPF
    ID gène
    22339
    UniProt
    Q00731
    Pathways
    Signalisation RTK, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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