GRM8 anticorps (C-Term)

N° du produit ABIN5531276

Cet anticorps Lapin Polyclonal détecte spécifiquement GRM8 dans WB. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour GRM8 anticorps (C-Term) (ABIN5531276)

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRM8 anticorps

Épitope: AA 852-882, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This Metabotropic Glutamate Receptor 8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 852-882 amino acids from the C-terminal region of human Metabotropic Glutamate Receptor 8.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GRM8

Antigène: GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))

Autre désignation: Metabotropic Glutamate Receptor 8

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Poids moléculaire: 102 kDa

ID gène: 2918

UniProt: O00222

Pathways: cAMP Metabolic Process, Synaptic Membrane