MORF4L2 anticorps (C-Term)

N° du produit ABIN5531605

Détail du produit anti-MORF4L2 anticorps

Antigène: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Épitope: AA 259-288, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MORF4L2 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MORF4L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human MORF4L2.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MORF4L2

Antigène: MORF4L2 (Mortality Factor 4 Like 2 (MORF4L2))

Autre désignation: MORF4L2 (MORF4L2 Produits)

Synonymes: anticorps morf4l2, anticorps MORF4L2, anticorps DKFZp468A0820, anticorps MORFL2, anticorps MRGX, anticorps 2410017O14Rik, anticorps Mrgx, anticorps Sid393p, anticorps mKIAA0026, anticorps LRRG00119, anticorps mortality factor 4 like 1, anticorps mortality factor 4 like 2, anticorps morf4l1, anticorps MORF4L2, anticorps Morf4l2

Sujet: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.

Poids moléculaire: 32 kDa

ID gène: 9643

UniProt: Q15014

Pathways: Regulation of Muscle Cell Differentiation