This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This SIRPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-134 amino acids from the Central region of human SIRPB1.
SIRPB1
Reactivité: Humain
Hôte: Lapin
Polyclonal
FITC
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.45 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
SIRPB1
(Signal-Regulatory Protein beta 1 (SIRPB1))
anticorps CD172b, anticorps SIRP-BETA-1, anticorps SIRPB1, anticorps SIRPG, anticorps signal regulatory protein beta 1, anticorps signal-regulatory protein beta-1, anticorps signal-regulatory protein beta-1 isoform 3, anticorps SIRPB1, anticorps LOC458036, anticorps LOC458430, anticorps LOC485809, anticorps LOC715912, anticorps LOC100458151
Sujet
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].