CYP2R1 anticorps (C-Term)

N° du produit ABIN5534038

Détail du produit anti-CYP2R1 anticorps

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Épitope: AA 464-496, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2R1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-496 amino acids from the C-terminal region of human CYP2R1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CYP2R1

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Autre désignation: CYP2R1 (CYP2R1 Produits)

Synonymes: anticorps cytochrome P450 family 2 subfamily R member 1, anticorps cytochrome P450, family 2, subfamily R, polypeptide 1, anticorps cytochrome P450, family 2, subfamily r, polypeptide 1, anticorps CYP2R1, anticorps cyp2r1, anticorps Cyp2r1

Sujet: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.

Poids moléculaire: 57 kDa

ID gène: 120227

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D