This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This KCNN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human KCNN1.
KCNN1
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.45 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Antigène
KCNN1
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 1 (KCNN1))
anticorps KCNN1, anticorps kcnn1, anticorps si:ch211-200a16.1, anticorps sk1, anticorps hsk1, anticorps skca1, anticorps MGC145919, anticorps KCa2.1, anticorps SK1, anticorps SKCA1, anticorps hSK1, anticorps AI854248, anticorps potassium calcium-activated channel subfamily N member 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1b, anticorps potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1, anticorps small conductance calcium-activated potassium channel protein 1, anticorps potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1, anticorps KCNN1, anticorps kcnn1b, anticorps kcnn1, anticorps LOC100456154, anticorps Kcnn1
Sujet
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes.