NDST1 anticorps (C-Term)

N° du produit ABIN5534558

Détail du produit anti-NDST1 anticorps

Antigène: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Épitope: AA 820-849, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NDST1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NDST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NDST1

Antigène: NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))

Autre désignation: NDST1 (NDST1 Produits)

Synonymes: anticorps HSST, anticorps NST1, anticorps 1200015G06Rik, anticorps Hsst, anticorps NDST-1, anticorps fj47c03, anticorps ndst1, anticorps wu:fj47c03, anticorps NDST1, anticorps N-deacetylase and N-sulfotransferase 1, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b, anticorps N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog, anticorps NDST1, anticorps Ndst1, anticorps ndst1b, anticorps ndst1, anticorps ndst1.S

Sujet: NDST1 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.

Poids moléculaire: 101 kDa

ID gène: 3340

UniProt: P52848

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process