PARP12 anticorps (N-Term)

N° du produit ABIN5535000

Détail du produit anti-PARP12 anticorps

Antigène: PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))

Épitope: AA 312-344, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This Parp12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-344 amino acids from the N-terminal region of human Parp12.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PARP12

Antigène: PARP12 (Poly (ADP-Ribose) Polymerase Family, Member 12 (PARP12))

Autre désignation: Parp12 (PARP12 Produits)

Synonymes: anticorps ARTD12, anticorps MST109, anticorps MSTP109, anticorps ZC3H1, anticorps ZC3HDC1, anticorps 9930021O16, anticorps AA409132, anticorps AA536654, anticorps PARP-12, anticorps Zc3hdc1, anticorps PARP12, anticorps zc3h1, anticorps mst109, anticorps mstp109, anticorps zc3hdc1, anticorps si:ch211-227d19.2, anticorps poly(ADP-ribose) polymerase family member 12, anticorps poly (ADP-ribose) polymerase family, member 12, anticorps poly(ADP-ribose) polymerase family member 12 L homeolog, anticorps poly (ADP-ribose) polymerase family, member 12a, anticorps poly [ADP-ribose] polymerase 12, anticorps PARP12, anticorps Parp12, anticorps parp12.L, anticorps parp12a, anticorps parp12, anticorps LOC100561568

Sujet: Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

Poids moléculaire: 80 kDa

ID gène: 243771

UniProt: Q8BZ20