RHOB anticorps (AA 104-137)

N° du produit ABIN5535664

Détail du produit anti-RHOB anticorps

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Épitope: AA 104-137

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RHOB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:4000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.83 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RHOB

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Autre désignation: ARHB (RHOB Produits)

Synonymes: anticorps ARH6, anticorps ARHB, anticorps MST081, anticorps MSTP081, anticorps RHOH6, anticorps AA017882, anticorps Arh6, anticorps Arhb, anticorps RHO, anticorps arha, anticorps rhoa, anticorps wu:fj42e08, anticorps zgc:92206, anticorps rhob, anticorps xrhob, anticorps ras homolog family member B, anticorps ras homolog gene family, member Ab, anticorps ras homolog family member B S homeolog, anticorps RHOB, anticorps Rhob, anticorps rhoab, anticorps rhob.S

Sujet: ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.

Poids moléculaire: 22 kDa

ID gène: 388

UniProt: P62745