GBA3 anticorps (C-Term)

N° du produit ABIN5535689

Détail du produit anti-GBA3 anticorps

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Épitope: AA 296-325, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GBA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human GBA3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GBA3

Antigène: GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))

Autre désignation: GBA3 (GBA3 Produits)

Synonymes: anticorps im:6912508, anticorps CBG, anticorps CBGL1, anticorps GLUC, anticorps KLRP, anticorps glucosylceramidase beta 3, anticorps glucosidase, beta, acid 3 (gene/pseudogene), anticorps glucosidase, beta, acid 3 (cytosolic), anticorps cytosolic beta-glucosidase, anticorps glucosylceramidase beta 3 (gene/pseudogene), anticorps Gba3, anticorps gba3, anticorps GBA3, anticorps LOC100344458

Sujet: GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).

Poids moléculaire: 54 kDa

ID gène: 57733

UniProt: Q9H227