KCNQ3 anticorps (C-Term)

N° du produit ABIN5536326

Détail du produit anti-KCNQ3 anticorps

Antigène: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Épitope: AA 651-679, C-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ3 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This KCNQ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 651-679 amino acids from the C-terminal region of human KCNQ3.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.45 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KCNQ3

Antigène: KCNQ3 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

Autre désignation: KCNQ3 (KCNQ3 Produits)

Synonymes: anticorps KCNQ3, anticorps si:ch211-66b9.3, anticorps BFNC2, anticorps EBN2, anticorps KV7.3, anticorps potassium voltage-gated channel subfamily Q member 3, anticorps potassium voltage-gated channel, KQT-like subfamily, member 3, anticorps potassium voltage-gated channel, subfamily Q, member 3, anticorps KCNQ3, anticorps kcnq3, anticorps Kcnq3

Sujet: The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2).

Poids moléculaire: 97 kDa

ID gène: 3786

UniProt: O43525