This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This TOP3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B.
TOP3B
Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc
WB, IHC, IP, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
anticorps TOP3B1, anticorps top3b, anticorps DNA topoisomerase III beta, anticorps topoisomerase (DNA) III beta, anticorps DNA topoisomerase III beta L homeolog, anticorps TOP3B, anticorps Top3b, anticorps top3b.L
Sujet
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity, however, not all variants have been fully described.