UCHL5 anticorps (N-Term)

N° du produit ABIN5537675

Détail du produit anti-UCHL5 anticorps

Antigène: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Épitope: AA 56-87, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UCHL5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogène: This UCH37 (UCHL5) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-87 amino acids from the N-terminal region of human UCH37 (UCHL5).

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur UCHL5

Antigène: UCHL5 (Ubiquitin Carboxyl-terminal Hydrolase L5 (UCHL5))

Autre désignation: UCH37 (UCHL5 Produits)

Synonymes: anticorps zgc:85615, anticorps wu:fj17f09, anticorps uch37, anticorps cgi-70, anticorps DKFZp459M0513, anticorps 5830413B11Rik, anticorps Uch37, anticorps CGI-70, anticorps INO80R, anticorps UCH-L5, anticorps UCH37, anticorps ubiquitin carboxyl-terminal hydrolase L5, anticorps ubiquitin C-terminal hydrolase L5, anticorps ubiquitin C-terminal hydrolase L5 L homeolog, anticorps ubiquitin carboxyl-terminal esterase L5, anticorps uchl5, anticorps UCHL5, anticorps uchl5.L, anticorps Uchl5

Sujet: Covalent attachment of the C-terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs). Mayer and Wilkinson (1989) identified 4 distinct UCH activities from bovine thymus. All 4 were thiol proteases and had high-affinity binding sites for ubiquitin. Wilkinson et al. (1989) purified the predominant isozyme, UCHL3, and raised antibodies against it. By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. Sequence comparisons revealed that the sequence of the predicted 230-amino acid human UCHL3 protein is 54 % identical to that of UCHL1.

Poids moléculaire: 38 kDa

ID gène: 51377

UniProt: Q9Y5K5