FIG4 anticorps (C-Term)

N° du produit ABIN5538449

Détail du produit anti-FIG4 anticorps

Antigène: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Épitope: AA 846-874, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FIG4 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-874 amino acids from the C-terminal region of human FIG4.

Isotype: Ig Fraction

Information d'application

Indications d'application: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur FIG4

Antigène: FIG4 (FIG4 Homolog, SAC1 Lipid Phosphatase Domain Containing (FIG4))

Autre désignation: FIG4 (FIG4 Produits)

Synonymes: anticorps A530089I17Rik, anticorps AI326867, anticorps Sac3, anticorps ALS11, anticorps CMT4J, anticorps KIAA0274, anticorps SAC3, anticorps YVS, anticorps dJ249I4.1, anticorps Kiaa0274, anticorps RGD1311375, anticorps FIG4 phosphoinositide 5-phosphatase, anticorps Fig4, anticorps FIG4

Sujet: The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

Poids moléculaire: 104 kDa

ID gène: 9896

UniProt: Q92562

Pathways: Inositol Metabolic Process