Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) anticorps

N° du produit ABIN5540300

Cet anticorps Souris Monoclonal détecte spécifiquement dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Dual Specificity Phosphatase 3 (DUSP3) (AA 1-185) anticorps (ABIN5540300)

Antigène: Dual Specificity Phosphatase 3 (DUSP3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT9E6

Détail du produit

Épitope: AA 1-185

Purification: Protein-A affinity chromatography

Immunogène: Recombinant human DUSP3 (1-185aa) purified from E. coli.

Isotype: IgG2b

Information d'application

Indications d'application: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution for Western blot analysis is 1:3000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. In Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détail du antigène

Antigène: Dual Specificity Phosphatase 3 (DUSP3)

Autre désignation: dusp3

Sujet: DUSP3, also known as Dual specificity protein phosphatase 3, is ictivate their target kises by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kise superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kises, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

UniProt: P51452

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades