Staphylococcus Aureus Enterotoxin Type B anticorps

N° du produit ABIN5542128

Détail du produit anti-Staphylococcus Aureus Enterotoxin Type B anticorps

Antigène: Staphylococcus Aureus Enterotoxin Type B

Reactivité: Staphylococcus aureus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Staphylococcus Aureus Enterotoxin Type B est non-conjugé

Application: Enzyme Immunoassay (EIA)

Specificité: Staphylococcal Enterotoxin B (SEB).

Purification: Affinity Chromatography on Protein G

Immunogène: SEB purified from Staphylococcus aureus.

Clone: SEB

Isotype: IgG1

Information d'application

Indications d'application: ELISA. This Staphylococcal Enterotoxin B (Clone SEB) as a superantigen for T-lymphocytes is a potential targeting antigen in cancer immunotherapy. It has been suggested that monoclonal antibody to SEB has been useful in immunotherapy research.

Restrictions: For Research Use only

Stockage

Buffer: 0.01M PBS, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Staphylococcus Aureus Enterotoxin Type B

Antigène: Staphylococcus Aureus Enterotoxin Type B

Autre désignation: staphylococcus aureus enterotoxin b (Staphylococcus Aureus Enterotoxin Type B Produits)

Sujet: Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus. The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway. Ingestion of SEB contaminated food is the common cause of "food poisoning", manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps. In severe cases, SEB can cause respiratory failure and systemic toxic shock. These symptoms are the results of increased membrane permeability and abnormal activation of Tlymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 Tcells activation and cytokine production. If unchecked, the process can result in systemic organ failure and death.

UniProt: P01552