MAPK10 anticorps (AA 180-329)
Aperçu rapide pour MAPK10 anticorps (AA 180-329) (ABIN5542487)
Antigène
Voir toutes MAPK10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 180-329
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Fonction
- MAPK10 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human MAPK10 (AA: 180-329) expressed in E. Coli.
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Isotype
- IgG2a
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Indications d'application
- ELISA: 1/10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))
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Autre désignation
- MAPK10
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Sujet
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
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Poids moléculaire
- 52.6 kDa
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UniProt
- P53779
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Pathways
- Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
Antigène
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