APBA2 anticorps (AA 15-158)

N° du produit ABIN5542600

Détail du produit anti-APBA2 anticorps

Antigène: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Épitope: AA 15-158

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APBA2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. coli.

Clone: 7G5G11

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Détails sur APBA2

Antigène: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Autre désignation: APBA2 (APBA2 Produits)

Synonymes: anticorps MGC83599, anticorps D15S1518E, anticorps HsT16821, anticorps LIN-10, anticorps MGC:14091, anticorps MINT2, anticorps X11-BETA, anticorps X11L, anticorps X11-like, anticorps XllL, anticorps mXllL, anticorps Mint2, anticorps amyloid beta precursor protein binding family A member 2, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog, anticorps amyloid beta (A4) precursor protein-binding, family A, member 2, anticorps APBA2, anticorps apba2.L, anticorps Apba2

Sujet:

Description: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.,

Aliases: X11L, MINT2, LIN-10, HsT16821, X11-BETA, D15S1518E, MGC:14091

Poids moléculaire: 82.5 kDa

ID gène: 321

HGNC: 699

Pathways: Synaptic Vesicle Exocytosis