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PARP1 anticorps (AA 1-100)

PARP1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 3G4 unconjugated
N° du produit ABIN559798
  • Antigène Voir toutes PARP1 Anticorps
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Épitope
    • 20
    • 18
    • 16
    • 15
    • 12
    • 10
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivité
    • 239
    • 68
    • 51
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 221
    • 34
    • 1
    • 1
    Souris
    Clonalité
    • 208
    • 49
    Monoclonal
    Conjugué
    • 150
    • 17
    • 16
    • 16
    • 15
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PARP1 est non-conjugé
    Application
    • 166
    • 129
    • 69
    • 44
    • 34
    • 29
    • 28
    • 28
    • 24
    • 17
    • 16
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Fonction
    Mouse monoclonal antibody raised against a partial recombinant PARP1.
    Séquence
    MAESSDKLYR VEYAKSGRAS CKKCSESIPK DSLRMAIMVQ SPMFDGKVPH WYHFSCFWKV GHSIRHPDVE VDGFSELRWD DQQKVKKTAE AGGVTGKGQD
     Réactivité croisée
    Humain
    Attributs du produit
    Antibody Reactive Against Recombinant Protein.
    Immunogène
    PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    3G4
    Isotype
    IgG2a
    Top Product
    Discover our top product PARP1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Conseil sur la manipulation
    Aliquot to avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Faraoni, Compagnone, Lavorgna, Angelini, Cencioni, Piras, Panetta, Ottone, Dolci, Venditti, Graziani, Lo-Coco: "BRCA1, PARP1 and ?H2AX in acute myeloid leukemia: Role as biomarkers of response to the PARP inhibitor olaparib." dans: Biochimica et biophysica acta, Vol. 1852, Issue 3, pp. 462-72, (2015) (PubMed).

    Nicolae, Aho, Vlahos, Choe, De, Karras, Moldovan: "The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance." dans: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13627-37, (2014) (PubMed).

    Shen, Oswald, Phelps, Cam, Pelloski, Pang, Houghton: "Regulation of FANCD2 by the mTOR pathway contributes to the resistance of cancer cells to DNA double-strand breaks." dans: Cancer research, Vol. 73, Issue 11, pp. 3393-401, (2013) (PubMed).

    Luijsterburg, Lindh, Acs, Vrouwe, Pines, van Attikum, Mullenders, Dantuma: "DDB2 promotes chromatin decondensation at UV-induced DNA damage." dans: The Journal of cell biology, Vol. 197, Issue 2, pp. 267-81, (2012) (PubMed).

    Pines, Vrouwe, Marteijn, Typas, Luijsterburg, Cansoy, Hensbergen, Deelder, de Groot, Matsumoto, Sugasawa, Thoma, Vermeulen, Vrieling, Mullenders: "PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1." dans: The Journal of cell biology, Vol. 199, Issue 2, pp. 235-49, (2012) (PubMed).

    Crawford, Yang, Mattaini, Hunter: "The metastasis efficiency modifier ribosomal RNA processing 1 homolog B (RRP1B) is a chromatin-associated factor." dans: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28660-73, (2009) (PubMed).

  • Antigène
    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
    Autre désignation
    PARP1 (PARP1 Produits)
    Synonymes
    anticorps ADPRT, anticorps ADPRT 1, anticorps ADPRT1, anticorps ARTD1, anticorps PARP, anticorps PARP-1, anticorps PPOL, anticorps pADPRT-1, anticorps Adprt, anticorps Parp-1, anticorps 5830444G22Rik, anticorps AI893648, anticorps Adprp, anticorps Adprt1, anticorps C80510, anticorps parp-1, anticorps sPARP-1, anticorps BEST:LD21673, anticorps CG17685, anticorps CG17696, anticorps CG17718, anticorps CG40411, anticorps D.PARP, anticorps Dm.pARTa, anticorps Dmel\\CG40411, anticorps LD21673.3prime, anticorps PARP1, anticorps dPARP, anticorps parp, anticorps adprt1, anticorps padprt-1, anticorps ppol, anticorps si:dkey-206f10.3, anticorps wu:fc60f12, anticorps zgc:110092, anticorps poly(ADP-ribose) polymerase 1, anticorps poly (ADP-ribose) polymerase 1, anticorps poly (ADP-ribose) polymerase family, member 1, anticorps Poly-(ADP-ribose) polymerase, anticorps poly(ADP-ribose) polymerase 1 L homeolog, anticorps PARP1, anticorps Parp1, anticorps Parp, anticorps parp1.L, anticorps parp1
    Sujet
    Full Gene Name: poly (ADP-ribose) polymerase 1
    Synonyms: ADPRT,ADPRT1,PARP,PARP-1,PPOL,pADPRT-1
    ID gène
    142
    Pathways
    Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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