CTH anticorps (AA 1-405)

N° du produit ABIN560522

Il existe 5+ publications pour ce produit. L’anticorps anti-CTH Monoclonal Souris est utilisé pour la détection de CTH dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour CTH anticorps (AA 1-405) (ABIN560522)

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTH est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 2E12-1C10

Détail du produit anti-CTH anticorps

Épitope: AA 1-405

Fonction: Mouse monoclonal antibody raised against a full length recombinant CTH.

Séquence: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-CTH (ABIN560522)

Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

Dickhout, Carlisle, Jerome, Mohammed-Ali, Jiang, Yang, Mani, Garg, Banerjee, Kaufman, Maclean, Wang, Austin: "Integrated stress response modulates cellular redox state via induction of cystathionine ?-lyase: cross-talk between integrated stress response and thiol metabolism." dans: The Journal of biological chemistry, Vol. 287, Issue 10, pp. 7603-14, (2012) (PubMed).

Maclean, Sikora, Kožich, Jiang, Greiner, Kraus, Krijt, Overdier, Collard, Brodsky, Meltesen, Crnic, Allen, Stabler, Elleder, Rozen, Patterson, Kraus: "A novel transgenic mouse model of CBS-deficient homocystinuria does not incur hepatic steatosis or fibrosis and exhibits a hypercoagulative phenotype that is ameliorated by betaine treatment." dans: Molecular genetics and metabolism, Vol. 101, Issue 2-3, pp. 153-62, (2010) (PubMed).

dEmmanuele di Villa Bianca, Sorrentino, Maffia, Mirone, Imbimbo, Fusco, De Palma, Ignarro, Cirino: "Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 11, pp. 4513-8, (2009) (PubMed).

Zhang, Jiang, Fang, Yan, Song, Gupta, Schafer, Durante, Kruger, Yang, Wang: "Hyperhomocysteinemia promotes inflammatory monocyte generation and accelerates atherosclerosis in transgenic cystathionine beta-synthase-deficient mice." dans: Circulation, Vol. 120, Issue 19, pp. 1893-902, (2009) (PubMed).

Détails sur CTH

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: CTH

Sujet: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

ID gène: 1491

Pathways: ER-Nucleus Signaling, L'effet Warburg