FGFR2 anticorps (AA 621-723)

N° du produit ABIN560876

L’anticorps Souris Monoclonal anti-FGFR2 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter FGFR2 dans des échantillons de Humain. Il y a 7+ publications disponibles.

Aperçu rapide pour FGFR2 anticorps (AA 621-723) (ABIN560876)

Antigène: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1G3

Détail du produit anti-FGFR2 anticorps

Épitope: AA 621-723

Fonction: Mouse monoclonal antibody raised against a partial recombinant FGFR2.

Séquence: GHRMDKPANC TNELYMMMRD CWHAVPSQRP TFKQLVEDLD RILTLTTNEE YLDLSQPLEQ YSPSYPDTRS SCSSGDDSVF SPDPMPYEPC LPQYPHINGS VKT

Specificité: This antibody cross-reacts with human FGFR1 and human FGFR3.

Réactivité croisée: Humain

Réactivité croisée (Details): This antibody cross-reacts with human FGFR1 and human FGFR3.

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: FGFR2 (AAH39243, 621 a.a. ~ 723 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-FGFR2 (ABIN560876)

Czaplinska, Mieczkowski, Supernat, Skladanowski, Kordek, Biernat, Zaczek, Romanska, Sadej: "Interactions between FGFR2 and RSK2-implications for breast cancer prognosis." dans: Tumour biology, Vol. 37, Issue 10, pp. 13721-13731, (2016) (PubMed).

Katano, Yamada: "Upregulation of ANGPTL4 messenger RNA and protein in severely calcified carotid plaques." dans: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 23, Issue 5, pp. 933-47, (2014) (PubMed).

Lee, Seo, Park, Kim, Park, Yu, Ahn, Gong: "Low prognostic implication of fibroblast growth factor family activation in triple-negative breast cancer subsets." dans: Annals of surgical oncology, Vol. 21, Issue 5, pp. 1561-8, (2014) (PubMed).

Cazet, Charest, Bennett, Sambrooks, Contessa: "Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity." dans: PLoS ONE, Vol. 9, Issue 10, pp. e110345, (2014) (PubMed).

Grygielewicz, Dymek, Bujak, Gunerka, Stanczak, Lamparska-Przybysz, Wieczorek, Dzwonek, Zdzalik: "Epithelial-mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells." dans: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, (2014) (PubMed).

Ozawa, Yang, Ealy: "The expression of fibroblast growth factor receptors during early bovine conceptus development and pharmacological analysis of their actions on trophoblast growth in vitro." dans: Reproduction (Cambridge, England), Vol. 145, Issue 2, pp. 191-201, (2013) (PubMed).

Vermeulen, Kornegoor, van der Wall, van der Groep, van Diest: "Differential expression of growth factor receptors and membrane-bound tumor markers for imaging in male and female breast cancer." dans: PLoS ONE, Vol. 8, Issue 1, pp. e53353, (2013) (PubMed).

Détails sur FGFR2

Antigène: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Autre désignation: FGFR2

Sujet: Full Gene Name: fibroblast growth factor receptor 2
Synonyms: BEK,BFR-1,CD332,CEK3,CFD1,ECT1,FLJ98662,JWS,K-SAM,KGFR,TK14,TK25

ID gène: 2263

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding