SLC11A2 anticorps (AA 1-65)

N° du produit ABIN562043

Détail du produit anti-SLC11A2 anticorps

Antigène: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Épitope: AA 1-65

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SLC11A2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against a partial recombinant SLC11A2.

Séquence: MVLGPEQKMS DDSVSGDHGE SASLGNINPA YSNPSLSQSP GDSEEYFATY FNEKISIPEE EYSCF

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: SLC11A2 (NP_000608, 1 a.a. ~ 65 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 4C6

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-SLC11A2 (ABIN562043)

Montalbetti, Simonin, Simonin, Awale, Reymond, Hediger: "Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2." dans: Biochemical pharmacology, Vol. 96, Issue 3, pp. 216-24, (2015) (PubMed).

Montalbetti, Simonin, Dalghi, Kovacs, Hediger: "Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra." dans: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 900-908, (2014) (PubMed).

Howitt, Putz, Lackovic, Doan, Dorstyn, Cheng, Yang, Chan-Ling, Silke, Kumar, Tan: "Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 36, pp. 15489-94, (2009) (PubMed).

Foot, Dalton, Shearwin-Whyatt, Dorstyn, Tan, Yang, Kumar: "Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2." dans: Blood, Vol. 112, Issue 10, pp. 4268-75, (2008) (PubMed).

Détails sur SLC11A2

Antigène: SLC11A2 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))

Autre désignation: SLC11A2 (SLC11A2 Produits)

Synonymes: anticorps DCT1, anticorps DMT1, anticorps NRAMP2, anticorps Nramp2, anticorps mk, anticorps van, anticorps Dmt1, anticorps ATNRAMP2, anticorps F8G22.4, anticorps F8G22_4, anticorps NRAMP metal ion transporter 2, anticorps dct1, anticorps dmt1, anticorps nramp2, anticorps SLC11A2, anticorps cb426, anticorps fa07b10, anticorps wu:fa07b10, anticorps zgc:136699, anticorps solute carrier family 11 member 2, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2, anticorps NRAMP metal ion transporter 2, anticorps manganese transport protein, anticorps metal transporter Nramp2, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2, anticorps SLC11A2, anticorps Slc11a2, anticorps NRAMP2, anticorps LOC9327403, anticorps slc11a2

Sujet: Full Gene Name: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Synonyms: DCT1,DMT1,FLJ37416,NRAMP2

ID gène: 4891

NCBI Accession: NM_000617

Pathways: Transition Metal Ion Homeostasis, Proton Transport, Positive Regulation of Endopeptidase Activity