BMP4 anticorps
Aperçu rapide pour BMP4 anticorps (ABIN5647052)
Antigène
Voir toutes BMP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Purification
- Antigen affinity purified
-
Immunogène
- A recombinant human protein corresponding to amino acids S293-R408 was used as the immunogen for the BMP4 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the BMP4 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, human recombinant protein): 0.1-0.5 μg/mL (BSA-free formulation available)
-
Restrictions
- For Research Use only
-
-
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- -20 °C
-
Stockage commentaire
- After reconstitution, the BMP4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
-
Autre désignation
- BMP4 / Bone morphogenetic protein 4
-
Sujet
- Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. It is found on chromosome 14q22-q23. The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
-
UniProt
- P12644
-
Pathways
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
Antigène
-