GAPDHS anticorps (AA 1-408)

N° du produit ABIN565269

Cet anticorps anti-GAPDHS est un anticorps Souris Monoclonal détectant GAPDHS dans WB, ELISA et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 12+ publications.

Aperçu rapide pour GAPDHS anticorps (AA 1-408) (ABIN565269)

Antigène: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GAPDHS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2E3-2E10

Détail du produit anti-GAPDHS anticorps

Épitope: AA 1-408

Fonction: Mouse monoclonal antibody raised against a full length recombinant GAPDS.

Séquence: MSKRDIVLTN VTVVQLLRQP CPVTRAPPPP EPKAEVEPQP QPEPTPVREE IKPPPPPLPP HPATPPPKMV SVARELTVGI NGFGRIGRLV LRACMEKGVK VVAVNDPFID PEYMVYMFKY DSTHGRYKGS VEFRNGQLVV DNHEISVYQC KEPKQIPWRA VGSPYVVEST GVYLSIQAAS DHISAGAQRV VISAPSPDAP MFVMGVNEND YNPGSMNIVS NASCTTNCLA PLAKVIHERF GIVEGLMTTV HSYTATQKTV DGPSRKAWRD GRGAHQNIIP ASTGAAKAVT KVIPELKGKL TGMAFRVPTP DVSVVDLTCR LAQPAPYSAI KEAVKAAAKG PMAGILAYTE DEVVSTDFLG DTHSSIFDAK AGIALNDNFV KLISWYDNEY GYSHRVVDLL RYMFSRDK

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: GAPDS (AAH36373, 1 a.a. ~ 408 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-GAPDHS (ABIN565269)

Kim, Hata, Kang: "Down-regulation of miR-96 by bone morphogenetic protein signaling is critical for vascular smooth muscle cell phenotype modulation." dans: Journal of cellular biochemistry, Vol. 115, Issue 5, pp. 889-95, (2014) (PubMed).

Kang, Davis-Dusenbery, Nguyen, Lal, Lieberman, Van Aelst, Lagna, Hata: "Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins." dans: The Journal of biological chemistry, Vol. 287, Issue 6, pp. 3976-86, (2012) (PubMed).

Kuravsky, Schmalhausen, Pozdnyakova, Muronetz: "Isolation of antibodies against different protein conformations using immunoaffinity chromatography." dans: Analytical biochemistry, Vol. 426, Issue 1, pp. 47-53, (2012) (PubMed).

Kang, Louie, Weisman, Sheu-Gruttadauria, Davis-Dusenbery, Lagna, Hata: "Inhibition of microRNA-302 (miR-302) by bone morphogenetic protein 4 (BMP4) facilitates the BMP signaling pathway." dans: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38656-64, (2012) (PubMed).

Chan, Weisman, Kang, Nguyen, Hickman, Mecker, Hill, Lagna, Hata: "The amiloride derivative phenamil attenuates pulmonary vascular remodeling by activating NFAT and the bone morphogenetic protein signaling pathway." dans: Molecular and cellular biology, Vol. 31, Issue 3, pp. 517-30, (2011) (PubMed).

Davis-Dusenbery, Chan, Reno, Weisman, Layne, Lagna, Hata et al.: "down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic ..." dans: The Journal of biological chemistry, Vol. 286, Issue 32, pp. 28097-110, (2011) (PubMed).

Chan, Hilyard, Wu, Davis, Hill, Lal, Lieberman, Lagna, Hata: "Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression." dans: The EMBO journal, Vol. 29, Issue 3, pp. 559-73, (2010) (PubMed).

Davis, Hilyard, Nguyen, Lagna, Hata: "Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha." dans: Molecular cell, Vol. 39, Issue 3, pp. 373-84, (2010) (PubMed).

Elkina, Kuravsky, Eldarov, Stogov, Muronetz, Schmalhausen: "Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase: structural basis for enhanced stability." dans: Biochimica et biophysica acta, Vol. 1804, Issue 12, pp. 2207-12, (2010) (PubMed).

Davis, Hilyard, Nguyen, Lagna, Hata: "Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype." dans: The Journal of biological chemistry, Vol. 284, Issue 6, pp. 3728-38, (2009) (PubMed).

Shchutskaya, Elkina, Kuravsky, Bragina, Schmalhausen: "Investigation of glyceraldehyde-3-phosphate dehydrogenase from human sperms." dans: Biochemistry. Biokhimii?a, Vol. 73, Issue 2, pp. 185-91, (2008) (PubMed).

Davis, Hilyard, Lagna, Hata: "SMAD proteins control DROSHA-mediated microRNA maturation." dans: Nature, Vol. 454, Issue 7200, pp. 56-61, (2008) (PubMed).

Détails sur GAPDHS

Antigène: GAPDHS (Glyceraldehyde-3-Phosphate Dehydrogenase, Spermatogenic (GAPDHS))

Autre désignation: GAPDHS

Sujet: Full Gene Name: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
Synonyms: GAPD2,GAPDH-2,GAPDS,HSD-35

ID gène: 26330

Pathways: Regulation of Carbohydrate Metabolic Process