Recombinant CD11b anticorps

N° du produit ABIN5668175

Cet anticorps Souris Monoclonal détecte spécifiquement CD11b dans FACS et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CD11b anticorps (ABIN5668175)

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD11b est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 107

Détail du produit anti-CD11b anticorps

Fonction: Anti-Integrin α-M [107], Mouse IgG1, kappa

Specificité: This antibody binds to the MIDAS face of the A domain from integrin CD11b.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: Wild type (WT) recombinant CD11b.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 Molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD11b

Antigène: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Autre désignation: Integrin alpha-M

Sujet: CD11b, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, leukocyte adhesion receptor MO1, Neutrophil adherence receptor, complement receptor 3

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation