MAP2K7 anticorps (C-Term)

N° du produit ABIN5671373

Cet anticorps anti-MAP2K7 Polyclonal Lapin (ABIN5671373) détecte spécifiquement MAP2K7 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Mouton, Cobaye, Lapin, Boeuf (Vache), Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour MAP2K7 anticorps (C-Term) (ABIN5671373)

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Reactivité: Humain, Souris, Rat, Chien, Mouton, Cobaye, Lapin, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAP2K7 anticorps

Épitope: C-Term

Fonction: MAP2K7 Antibody - C-terminal region

Séquence: KDCLTKDHRK RPKYNKLLEH SFIKRYETLE VDVASWFKDV MAKTESPRTS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MP2K7. It was validated on Western Blot.

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49026-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MAP2K7

Sujet:

Background Information: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

Gene Name: mitogen-activated protein kinase kinase 7

Alternative Symbols: MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4

Protein Name: dual specificity mitogen-activated protein kinase kinase 7

Poids moléculaire: 50kDa

ID gène: 5609

UniProt: O14733

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling