HTR2A anticorps (AA 171-270) (Biotin)

N° du produit ABIN5675439

Cet anticorps Lapin Polyclonal détecte spécifiquement HTR2A dans WB et ELISA. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour HTR2A anticorps (AA 171-270) (Biotin) (ABIN5675439)

Antigène: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2A est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA

Détail du produit anti-HTR2A anticorps (Biotin)

Épitope: AA 171-270

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human 5HT2A Receptor

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur HTR2A

Antigène: HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

Autre désignation: 5HT2A Receptor

Sujet:

Synonyms: 5-hydroxytryptamine receptor 2A, HTR2A, 5-hydroxytryptamine receptor 2A, 5-HT-2, 5-HT-2A, Serotonin receptor 2A, HTR2A, HTR2

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD) (PubMed:28129538). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors (PubMed:28129538). Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways (PubMed:28129538). Signaling activates phospholipase C and a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and promotes the release of Ca2+ ions from intracellular stores (PubMed:18703043, PubMed:28129538). Affects neural activity, perception, cognition and mood (PubMed:18297054). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction.

ID gène: 8549

UniProt: P28223

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process