CIRBP anticorps (Internal Region)

N° du produit ABIN568701

Détail du produit anti-CIRBP anticorps

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Épitope: AA 81-91, Internal Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CIRBP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-QAGKSSDNRS R

Specificité: Recognizes CIRBP (aa 81-91).

Réactivité croisée (Details): Species reactivity (expected):Human, Dog, Cow.
Species reactivity (tested):Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_001271.1. Genename: CIRBP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CIRBP

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Autre désignation: CIRBP (CIRBP Produits)

Synonymes: anticorps CIRP, anticorps Cirp, anticorps R74941, anticorps Xcirp, anticorps cirbp, anticorps cirbp-a, anticorps cirbp2, anticorps cirp, anticorps cirp1, anticorps cirp2, anticorps xcirp2, anticorps XCIRP, anticorps XCIRP-1, anticorps cirbp-b, anticorps cirp-1, anticorps APBP-1, anticorps zgc:136559, anticorps CIRBP, anticorps A18 hnRNP, anticorps cold inducible RNA binding protein, anticorps cold-inducible RNA-binding protein, anticorps cold inducible RNA binding protein S homeolog, anticorps cold inducible RNA binding protein L homeolog, anticorps cold inducible RNA binding protein b, anticorps CIRBP, anticorps EDI_107320, anticorps Cirbp, anticorps cirbp.S, anticorps cirbp.L, anticorps cirbp, anticorps cirbpb

Sujet: CIRBP, also named as A18HNRNP and CIRP, is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP is also involved in cap-independent translation upon moderate cold-shock. It acts as a translational activator. CIRBP is a suppressive rather stimulatory effect on proliferation. It acts as a translational repressor. CIRBP is an immortalized gene in murine primary cells. CIRBP promotes assembly of stress granules (SGs), when overexpressed. It is a potential proto-oncogenic proteins upon overexpression. Suppression of CIRBP increased the apoptotic cell population of neural stem cells at moderate low temperature.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

ID gène: 1153

NCBI Accession: NP_001271

UniProt: Q14011

Pathways: Ribonucleoprotein Complex Subunit Organization