CDC25C anticorps (AA 214-218)
Aperçu rapide pour CDC25C anticorps (AA 214-218) (ABIN5689442)
Antigène
Voir toutes CDC25C AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 214-218
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Specificité
- This antibody detects endogenous level of total cdc25C protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogène
- cdc25C (Ab-216) antibody was raised against a peptide sequence around aa.214~218 (S-P-S-M-P) derived from Human cdc25C.
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Indications d'application
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store antibody at -20°C for up to one year.
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- CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))
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Autre désignation
- cdc25C
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Sujet
- Cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encodedprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
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Poids moléculaire
- 60 kDa
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ID gène
- 995
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NCBI Accession
- NP_001781
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UniProt
- P30307
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Pathways
- Cycle Cellulaire, M Phase
Antigène
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