APOBEC3B anticorps (Apolipoprotein B MRNA Editing Enzyme, Catalytic Polypeptide-Like 3B) (AA 20-70)

Details for Product anti-APOBEC3B Antibody No. ABIN5689877, Fournisseur: Connectez-vous pour afficher
Antigène
  • APOBEC3H
  • APOBEC3B
  • A3B
  • APOBEC1L
  • ARCD3
  • ARP4
  • DJ742C19.2
  • PHRBNL
  • bK150C2.2
  • APOBEC3F
  • APOBEC3Z2
  • APOBEC3Z3
  • Apobec3
  • Apobec3f
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3
  • apolipoprotein B mRNA editing enzyme catalytic subunit 3B
  • apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
  • APOBEC3Z3
  • APOBEC3B
  • APOBEC3Z2
  • Apobec3b
Épitope
AA 20-70
15
8
8
7
7
3
3
1
1
Reactivité
Humain, Souris, Rat (Rattus)
54
12
4
1
1
1
1
1
1
Hôte
Lapin
51
3
Clonalité
Polyclonal
Conjugué
Cet anticorp APOBEC3B est non-conjugé
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
41
23
13
7
6
3
3
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène APOBEC3B antibody was raised against a 14 amino acid peptide near the amino terminus of human APOBEC3B.

The immunogen is located within amino acids 20 - 70 of APOBEC3B.
Isotype IgG
Specificité APOBEC3B antibody is human, mouse and rat reactive . At least three isoforms of APOBEC3B are known to exist, this antibody will detect all three. APOBEC3B antibody may cross-react with APOBEC3D.
Purification APOBEC3B antibody is affinity chromatography purified via peptide column.
Plasmids, Primers & others Plasmids, Primers & others APOBEC3B products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation APOBEC3B (APOBEC3B Antibody Extrait)
Sujet The Apolipoprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytosine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates (1). Similar to TRIM5? which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection (2,3). APOBEC3B has also been shown to be upregulated in several cancers, it is thought that APOBEC3B-catalyzed genomic uracil lesions are responsible for a large proportion of mutations in multiple distinct cancers (4).
Poids moléculaire Predicted: 42 kDa

Observed: 48 kDa
ID gène 9582
NCBI Accession NP_004891
UniProt Q9UH17
Indications d'application APOBEC3B antibody can be used for detection of APOBEC3B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer APOBEC3B Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire APOBEC3B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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