SNRPE anticorps (AA 330-380)

N° du produit ABIN5689894

Détail du produit anti-SNRPE anticorps

Antigène: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Épitope: AA 330-380

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRPE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least two isoforms of B-raf are known to exist, this antibody will detect both isoforms. This antibody will not cross-react with C-raf.

Purification: B-raf Antibody is affinity chromatography purified via peptide column.

Immunogène: B-raf antibody was raised against a 19 amino acid peptide near the center of human B-raf.

The immunogen is located within amino acids 330 - 380 of B-raf.

Isotype: IgG

Information d'application

Indications d'application: B-raf antibody can be used for detection of B-raf by Western blot at 1 and 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: B-raf Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: B-raf antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur SNRPE

Antigène: SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))

Autre désignation: B-raf (SNRPE Produits)

Synonymes: anticorps B-raf, anticorps HYPT11, anticorps SME, anticorps Sm-E, anticorps b-raf, anticorps sm-e, anticorps sme, anticorps SmE, anticorps snRNP-E, anticorps AL022645, anticorps C76690, anticorps zgc:56682, anticorps small nuclear ribonucleoprotein polypeptide E, anticorps small nuclear ribonucleoprotein polypeptide E L homeolog, anticorps small nuclear ribonucleoprotein E, anticorps SNRPE, anticorps snrpe.L, anticorps Snrpe, anticorps snrpe

Sujet: B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

Poids moléculaire: Predicted: 84

Observed: 99, multiple post-translational modifications, commonly observed at 95-100kDa

ID gène: 673

UniProt: P15056

Pathways: Ribonucleoprotein Complex Subunit Organization, Hepatitis C