×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
FGFR3 anticorps (AA 630-680)
FGFR3
Reactivité: Humain, Souris, Rat
WB, ELISA, IHC (p), IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN5689961
Détail du produit anti-FGFR3 anticorps
(cache)
Antigène
Voir toutes FGFR3 Anticorps
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
Épitope
Tous les épitopes à travers FGFR3 Anticorps.
AA 630-680
Reactivité
Toutes les réactivités sur FGFR3 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur FGFR3 Anticorps
Lapin
Clonalité
Toutes les clonalités sur FGFR3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers FGFR3 Anticorps
Cet anticorp FGFR3 est non-conjugé
Application
Tous les applications à travers FGFR3 Anticorps.
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Specificité
FGFR3 antibody is human, mouse and rat reactive. At least three isoforms of FGFR3 are known to exist, this antibody will detect all three.
Purification
FGFR3 Antibody is affinity chromatography purified via peptide column.
Immunogène
FGFR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3. The immunogen is located within amino acids 630 - 680 of FGFR3.
Isotype
IgG
Top Product
Discover our top product FGFR3 Anticorps primaire
Alternatives
(show)
Information d'application
(cache)
Indications d'application
FGF3 antibody can be used for detection of FGFR3 by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
FGFR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
FGFR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Détails sur FGFR3
(cache)
Antigène
FGFR3
(Fibroblast Growth Factor Receptor 3 (FGFR3))
Autre désignation
FGFR3 (FGFR3 Produits )
Synonymes
anticorps FGFR3, anticorps LOC100034114, anticorps ACH, anticorps CD333, anticorps CEK2, anticorps HSFGFR3EX, anticorps JTK4, anticorps FR3, anticorps Fgfr-3, anticorps Flg-2, anticorps HBGFR, anticorps Mfr3, anticorps sam3, anticorps fc27h01, anticorps wu:fc27h01, anticorps fibroblast growth factor receptor 3, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog, anticorps FGFR3, anticorps fgfr3.S, anticorps Fgfr3, anticorps fgfr3
Sujet
FGFR3 Antibody: FGFR3 is a tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis (1). It is required for normal skeleton development and promotes apoptosis in chondrocytes and cancer cell proliferation. FGFR3 protein contains three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain (1,2). It is alternatively spliced to produce three isoforms that are expressed in brain, kidney and testis. Defects in FGFR3 are associated with several diseases, including achondroplasia and hypochondroplasia (3,4). Mutations in FGFR3 are also a cause of some bladder and cervical cancers (5).
Poids moléculaire
Predicted: 89 kDa Observed: 9+2, 98 kDa
ID gène
2261
NCBI Accession
NP_001156685
UniProt
P22607
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Stem Cell Maintenance , Growth Factor Binding
Vus récemment
(cache)